In 2023, the Interstate Technology and Regulatory Council (ITRC) Contaminants of Emerging Concern (CEC) Framework was published to help environmental regulatory agencies and other stakeholders identify, evaluate, and manage CEC’s while acknowledging uncertainties in their environmental fate and transport, receptor exposure, and/or toxicity. The framework is meant to help environmental regulatory agencies and other stakeholders by providing examples of CEC monitoring programs and guiding the user through the process of identifying CEC key characteristics, how to communicate real and perceived risk from CEC to the public, and how laboratory analytical methods can be used in the identification process. This training by ITRC will discuss the framework in detail.