“An Overview of 6PPD-Quinone: Where We Started, Where We Are Now, and Where We Are Headed” was recorded at the 14th Annual SABCS Workshop & Conference on Contaminated Sites, September 25-26, in British Columbia, Canada. The presentation covers how researchers linked stormwater and tire chemicals to coho mortality and provides an overview of ongoing current research in the aquatic ecotoxicology lab at Washington State University. The search for alternatives to 6PPD and the regulatory actions being taken in the U.S. are also described.