6PPD is a common tire additive; 6PPD-quinone is a chemical by-product. On January 30, EPA published a draft testing method (EPA Method 1634) that will help Tribes, government agencies, and others determine where and when 6PPD-quinone is present in local stormwater and surface waters.

Used for more than six decades in tires, 6PPD is also found in other rubber products such as footwear, synthetic turf infill, and synthetic playground surfaces. 6PPD reacts with ozone in the air to form 6PPD-quinone, which EPA-funded research in 2020 found to be linked to the deaths of coho salmon in urban Puget Sound streams. Exposures occur when runoff containing the chemical is washed from parking lots and streets into streams and other bodies of water.